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Neuroscience Drug Discovery and Development: The Route to Disease-Modifying Therapies
from MIT Enterprise Forum - Cambridge
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Wednesday, November 12, 2008, 5:30pm - 9:00pm
Disorders of the brain, including neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease and psychiatric diseases such as schizophrenia and depression, pose some of the hardest challenges for the biopharmaceutical industry. The disease burden from brain disorders is enormous, and the commercial potential is correspondingly attractive to industry and its investors. However, complex pathophysiology, poor preclinical models, a lack of reliable biomarkers and expensive clinical trials all impede development of new therapies. Join us for a discussion of how the biopharmaceutical industry is addressing these challenges, with guest speakers from the cutting edge of neuroscience drug discovery.
Keynote Speaker:
Darryle D. Schoepp, Ph.D.
Senior Vice President and Franchise Head, Neuroscience
Merck Research Laboratories
Dr. Schoepp is responsible for the scientific direction of drug discovery and development for neuroscience programs at Merck. Prior to joining Merck he was a VP at Eli Lilly, where he led the development of a new first-in-class drug for the treatment of schizophrenia.
Company Presentation:
FoldRx Pharmaceuticals, Inc.
Christoph M. Adams, Ph.D., Chief Business Officer
FoldRx is a leader in the discovery and development of disease modifying drug therapies for diseases of protein misfolding and amyloidosis. Misfolded proteins are emerging as an underlying cause of many neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease, Huntington’s Disease and prion diseases. Dr. Susan Lindquist, Member, Whitehead Institute for Biomedical Research and Professor of Biology at MIT is a co-founder of the company.
Moderator:
Skip Irving, Partner and Managing Director, Health Advances LLC
Panel:
Douglas M. Fambrough, Ph.D.
General Partner
Oxford Bioscience Partners
Todd Sherer, Ph.D.
Vice President, Research Programs
The Michael J. Fox Foundation for Parkinson’s Research
Program Organizers:
Pearl Freier, Cambridge BioPartners, Skip Irving, Health Advances, Charles Jennings, Ph.D., The McGovern Institute for Brain Research at MIT, and Matthew P. Kowalsky, Choate Hall & Stewart LLP
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